Gene description for ACTA2
Gene name	actin alpha 2, smooth muscle
Gene symbol	ACTA2
Other names/aliases	ACTSA
Species	Homo sapiens
Experiment description of studies that identified ACTA2 in Prostate cancer cells
1 Experiment ID 136 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name PC3 - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
2 Experiment ID 137 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name PC3 - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
3 Experiment ID 140 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name VCaP - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
4 Experiment ID 142 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name LNCaP - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
5 Experiment ID 143 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name LNCaP - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
6 Experiment ID 144 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name C4-2 - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
7 Experiment ID 145 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name C4-2 - Rep 3 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
8 Experiment ID 146 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [QTOF]    Supporting data    MSS    PubMed ID 22723089    Organism Homo sapiens Experiment description Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Authors Hosseini-Beheshti E, Guns ES. Journal name MCP Publication year 2012 Sample Prostate cancer cells Sample name RWPE - Rep 2 Isolation/purification methods Sucrose density gradient Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK EV120018: EV-METRIC:38%
9 Experiment ID 277 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry [Q-TOF] PubMed ID 22030351    Organism Homo sapiens Experiment description Expression of PTRF in PC-3 cells modulates cholesterol dynamics and the actin cytoskeleton impacting secretion pathways Authors Inder KL, Zheng YZ, Davis MJ, Moon H, Loo D, Nguyen H, Clements JA, Parton RG, Foster LJ, Hill MM Journal name MCP Publication year 2011 Sample Prostate cancer cells Sample name PC-3 Isolation/purification methods Differential centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] EV-TRACK -
10 Experiment ID 1110 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name PC346C- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
11 Experiment ID 1111 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name PC346C- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
12 Experiment ID 1112 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name PC346C- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
13 Experiment ID 1113 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name VCaP- replicate 1 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
14 Experiment ID 1114 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name VCaP- replicate 2 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%
15 Experiment ID 1115 Identified molecule protein Extracellular vesicle type Exosomes MISEV EVs Identification method Mass spectrometry PubMed ID 24391718    Organism Homo sapiens Experiment description Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer. Authors Duijvesz D, Burnum-Johnson KE, Gritsenko MA, Hoogland AM, Vredenbregt-van den Berg MS, Willemsen R, Luider T, Pa.a-Toli. L, Jenster G. Journal name PLoS One Publication year 2013 Sample Prostate cancer cells Sample name VCaP- replicate 3 Isolation/purification methods Differential centrifugation Ultracentrifugation Density gradient centrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry EV-TRACK EV130038: EV-METRIC:33%